Source : https://dofollownet.com
Oct. 5, 2009 - STOCKHOLM: Elizabeth Blackburn, Carol W. Greider and Jack Szoztak deciphered the enigma of how chromosomes are protected by telomeres and the enzyme telomerase.
The Karolinska Institute has awarded this year's Nobel Prize in Physiology or Medicine to three US scientists (two women and one man) who solved one of the greatest mysteries of biology: how chromosomes can be copied in a complete way during cell divisions and how they are protected against degradation.
DNA molecules, the long chain formed by chemical letters that code the genes are packaged into chromosomes, capped by telomeres on their ends. Blackburn and Szostak found that a specific DNA sequence in the telomeres protects the chromosomes from degradation during cell division.
They also identified telomerase, the enzyme that produces telomeres DNA.
These discoveries by Blackburn, Greider and Szostak are closely related to the mechanisms of cell's aging and lay the groundwork for new therapeutic strategies against cancer and aging-related ailments.
Elizabeth H. Blackburn, born in Australia in 1948, works at the University of California, in San Francisco.
Carol W. Greider, born in the USA in 1961, works at Johns Hopkins University School of Medicine in Baltimore.
Jack W. Szostak, born in the UK in 1952, is a Howard Hughes Medical Institute investigator at Massachusetts General Hospital and Harvard Medical School.
More detailed information on this Howard Hughes Medical Institute web page.Read full article »